Dapakan

Generic Name: Divalproex Sodium Tabs 250mg & 500mg and Sodium Valproate Syrup 250mg/5ml

Packing: 10 x 10

Bottle: 120ml

Registration # 24464

Description

Dapakan Tablets contain divalproex sodium which is stable co-ordination compound comprised of sodium valproate and valproic acid in a 1:1 molar relationship. Dapakan tablets are supplied in two dosage strengths containing divalproex sodium equivalent to 250 mg and 500 mg of valproic acid.

Dapakan Syrup contains sodium valproate (B.P.) equivalent to valproic acid 250 / 5 ml.

Uses / Indications

Epilepsy Dapakan is indicated for use as sole and adjunctive therapy in the treatment of simple (petit mal) and complex absence seizures, as well as in generalized tonic clonic (grand mal) juvenile myoclonic and partial (focal, local) simple complex seizures. In accordance with the international classification of seizures, simple absence is defined as very brief clouding of the sensorium or loss of consciousness (lasting usually 2 – 15 seconds), accompanied by certain generalized epileptic discharges without other detectable clinical signs. Complex absence is the term used when other signs are also present.

Mania Dapakan tablets are indicated for the treatment of the manic episodes associated with bipolar disorder. A manic episode is a distinct period of abnormally and persistently elevated, expansive, or irritable mood. Typical symptoms of mania include pressure of speech motor hyperactivity reduced ‘need for sleep, flight of ideas, grandiosity, poor judgment, aggressiveness, and possible hostility. The safety effectiveness of Dapakan for long term use in mania, i.e. more than three weeks, has not been systematically evaluated in controlled clinical trials. Therefore physicians who elect to use Dapakan for extended periods should continually reevaluate the long-term usefulness of the drugs for the individual patient.

Migraine Dapakan tablets are indicated for prophylaxis of migraine headaches. There is no evidence that Dapakan is useful in the acute treatment of migraine headaches. Because valproic acid may be a hazard to the fetus. Dapakan should be considered for women of childbearing potential only after risk has been thoroughly discussed with the patient and weighted against the potential benefits of treatment (See WARNINGS-USage in Pregnancy).