CYCLODEX
Generic Name: Piroxicam Beta Cyclodextrin Tab 20mg
Packing: 2 x 10
Registration # 24446
Description
Each tablet contains :
Piroxicam-B-Cyclodextrin………….191.2mg
eq to piroxicam (USP) ……………20mg
Product Complies Platinum Specs. Cyclodex is a new formulation of piroxicam as a complex with B-cyclodextrin in the molar ratio 1:2.5. B-cyclodextrin, produced by enzymatic hydrolysis of common starch, has a particular chemical structure that enables it to form inclusion compounds (molecular encapsulation) with various drugs. In this way it is able to improve solubility, stability and bioavailability. Cyclodex is very soluble in water and has a more rapid and complete absorption than plain piroxicam after oral or rectal administration. The improved solubility leads to a rapid increase in plasma levels and peak value is reached earlier. In clinical terms this means a quicker and more intense analgesic and anti-inflammatory effect. The long half life of Cyclodex, which is the same as that of plain piroxicam, allows for just one single daily dose. Due to its pharmacodynamic and pharmacokinetic properties, Cyclodex is particularly suitable for the treatment of rheumatic and/or inflammatory disorders with painful symptoms that could seriously affect the general conditions and normal activity of patients and where a rapid and intense efficacy is required.
Uses / Indications
Acute painful conditions
Each tablet contains :
Piroxicam-B-Cyclodextrin………….191.2mg
eq to piroxicam (USP) ……………20mg
Product Complies Platinum Specs. Cyclodex is a new formulation of piroxicam as a complex with B-cyclodextrin in the molar ratio 1:2.5. B-cyclodextrin, produced by enzymatic hydrolysis of common starch, has a particular chemical structure that enables it to form inclusion compounds (molecular encapsulation) with various drugs. In this way it is able to improve solubility, stability and bioavailability. Cyclodex is very soluble in water and has a more rapid and complete absorption than plain piroxicam after oral or rectal administration. The improved solubility leads to a rapid increase in plasma levels and peak value is reached earlier. In clinical terms this means a quicker and more intense analgesic and anti-inflammatory effect. The long half life of Cyclodex, which is the same as that of plain piroxicam, allows for just one single daily dose. Due to its pharmacodynamic and pharmacokinetic properties, Cyclodex is particularly suitable for the treatment of rheumatic and/or inflammatory disorders with painful symptoms that could seriously affect the general conditions and normal activity of patients and where a rapid and intense efficacy is required.
